2006-2007 Issue

Academic Promotion

Drs. Neil Fleshner and Joao Pippi-Salle were promoted to Professor.

Royal College Review

The External review took place on April 18, 2007. The division obtained full approval with no concerns identified.

Hospital Highlights

The Hospital for Sick Children

The Campbell-Walsh chapter on Reflux and Megaureter written by Drs. Tony Khoury and Darius Bagli was published.

Dr. Darius Bagli received funding for his project entitles Epigenetic changes in uroepitelium following e.coli infection: new keys to understanding urinary tract infection susceptibility from the Hospital for Sick Children – Research Institute. He was also the invited keynote speaker at the Pan-Arab Continence Society Annual Meeting, Manama, Bahrain in November.

Dr. Walid Farhat continued his work in tissue engineering and with K. Derwin were funded by the Cleveland Clinic Foundation (Biomedical Research and Technology Transfer Program-part of Ohio’s Third Frontier Initiative) for their project entitled Biologically Enhanced Fascia Lata Graft for Soft Tissue Repair. Dr. Farhat was also a guest speaker at conferences in Banff, Beirut Lebanon, Cairo Egypt, and Nashville Tennessee.

Dr. Tony Khoury continued a site chief at Sick Kids. He also continued his peer reviewed research and was invited to lecture in Cape Town, South Africa, Brugge Belgium, and at Columbia University in New York City.

Dr. Joao Pippi-Salle was an invited speaker, surgeon, and visiting professor in many locations around the worls. These included Madrid, Spain, Cape Town, South Africa, New Dehli, India, the University of Arkansas, Little Rock, Arkansas, Rio de Janeiro, Brazil, Parma, Italy, Bologna, Italy, Marrakesh, Morocco, Casablanca, Morocco, and the University of British Columbia, Vancouver, BC. He also continued as Director of Continuing Professional Development for the Department of Surgery. He chaired the 2nd Annual Urology Symposium which was on Hypospadias this year.

Dr. Armando Lorenzo continued his work in Clinical Epidemiology and minimally invasive pediatric surgery.

Mount Sinai Hospital

Dr. Keith Jarvi, site chief at MSH, continued the Male Infertility Program and as Director of the The Murray Koffler Urologic Wellness Centre (MKUWC). Dr. Jarvi again organized the Annual Robson Research Day Resident and Fellow scientific presentation contest. He was an invited speaker in Ottawa, ON, Kingston, ON, and at the University of Rochester, Rochester, New York.

He received funding for his project entitled: Use of seminal fluid protein patterns as biomarkers for diseases in the male reproductive tract: Prediction of spermatogenesis in men with azoospermia, from Physicians Services Incorporated. His co-investigators are K. Lo, E. Diamandis, and B. Mullen. He also part of a CIHR grant on the genetics of male infertility.

Dr. Kirk Lo continued his basic infertility research in stem cells. He presented at the plenary session at the AUA annual meeting in Anaheim CA, and chaired an educational forum at the CUA annual meeting in Quebec City.

Dr. Alexandre Zlotta started as a Uro-oncologist in the Divisions at MSH and PMH. He continued his position as Associate Editor of European Urology, one of the premier international journals in urology. On January 18th he was awarded PhD with the official title of “Docteur en Sciences Medicales” by the Free University of Brussels, Belgium. His theses were “BCG immunotherapy for superficial bladder cancer: further insights into its mechanism of action”, and “Place du PSA et des parametres volumetriques dans la detection du cancer de prostate.”
He received a funding award from the Canadian Prostate Cancer Research foundation for his project entitled: Prevalence and age distribution of Prostate Carcinoma and its precursor lesions in African, Asian and Caucasian men in autopsy specimens: a prospective comparative international study. Co-investigators are Neil Fleshner, Keith Jarvi, Theo Van der Kwast, and Tony Finelli. International collaboration is with Italy, Spain, Russia, Japan, and Congo. He also received a non peer-reviewed research grant from Sanofi-Aventis for prostate cancer research.

He was visiting professor at the University of Tokyo, Tokyo, Japan, and invited speaker at the South African Congress of Urology, European Residents Program, Prague, Czech Republic, and at meetings in Paris, France, Berlin, Germany, and Nijmegen, Netherlands. He was the member for urology Prevention Initiative of the NCIC meeting in Vancouver, BC.

Sunnybrook

Dr. Lesley Carr continued her work as an investigator in an NIH grant to evaluate the efficacy of amitriptyline for the treatment of painful bladder syndrome, and in an industry grant for the use of muscle stem cells in stress urinary incontinence. Dr. Carr was in charge of Journal Seminars for Urology residents.

Dr. Sender Herschorn was named as the first Chairholder of the Martin Barkin Chair in Urological Research. This is a university chair that will be held by the division chair. He continued his clinical research in urinary incontinence, neurogenic bladder overactivity, and erectile dysfunction. He was invited speaker and lecturer at the University of Western Ontario, London, ON, Dalhousie University, Halifax, NS, Christchurch, NZ, Berlin, Germany, Anaheim, CA, and Sudbury, ON. The chapter he authored on Vaginal Reconstructive Surgery in the new Campbell-Walsh textbook of Urology was published. He also won W.T. Aikins Faculty Teaching Award for Excellence in Undergraduate Teaching: for individual teaching performance (small group). He also directed the 14th annual U of T Urology Update.
Dr. Laurence Klotz, site chief at Sunnybrook, continued his research in Uro-oncology and his many leadership appointments including Editor-in-chief of the new Canadian Urological Association Journal. He continued as Chair of the Canadian Urology Research Consortium the World Uro Oncology Federation, (WUOF), an organization of 12 national and regional Uro Oncology Societies around the world.

He continued his many peer-reviewed research projects as well as initiated new work in prostate cancer treatment and prevention. He was guest speaker and visiting professor in Anaheim, CA, Chicago, IL, Santo Domingo, DR, University of South Florida, Sarasota, FL, Syracuse University, Syracuse, NY, Baylor University, Dallas, TX. He was invited guest speakers by Urological Societies of Quebec, Japan, Mexico, and Australia and New Zealand. He won the 2006 Richard Lafferty Excellence in Writing Award from the Ontario Society of Medical Technologists. He was also elected as a member of the American Association of Genitourinary Surgeons.

Dr. Ron Kodama completed 10 years as Program Director for the Division and was honoured by his current and former students at a dinner at the Urology Fair in February. He again organized the 4th Annual Resident Basic Science Course in February. He again organized the Surgical Skills Lab sessions on TURP and TURBT. He also directed the annual Urology Fair 2007. He also won the Division of Urology Postgraduate Clinical Teaching Award.

Dr. Robert Nam continued his research in the genetics of prostate cancer. He was an invited speaker at the SIU GU Oncology conference in Cape Town, South Africa, at an educational forum at the CUA in Quebec City. He continued his work on his peer-reviewed projects from NCIC and received new research awards from CIHR for his project entitled: Individual risk assessment for prostate cancer using risk factors, tumour markers and new biomarkers, (with S. Narod) and from the NCIC for “Cross-Canada assessment of a new nomogram prediction tool for prostate cancer screening” with co-investigators from across Canada. He received the Division of Urology Faculty Postgraduate Surgical Teaching Award and the Peter’s Boyd Academy Clinical Teaching Supervision Award.

Dr. Sharon Sharir continued her work in studying outcomes in women’s and men’s experiences with radical cystectomy for bladder cancer. Dr. Sharir ended her stay at Sunnybrook and went into practice at Humber Hospital.

Dr. Vasundara Venkateswaran continued her basic research in the peer-reviewed prostate cancer project on a transgenic mouse prostate cancer prevention model. She also received new CIHR and PCRFC awards as PI for prostate cancer research. She is also a co-investigator on 2 grants from one from the NCIC (with Dr. Michael Pollak, McGill) and the other from CPCRI (Dr. Bharati Bapat, MSH). She also supervises a PhD student and clinical fellow in her lab.

UHN – Toronto General Hospital and Princess Margaret Hospital

Dr. Neil Fleshner, site chief at the UHN, was appointed Professor. He continued his clinical and basic research in prostate cancer with many major peer-reviewed grants from CIHR, NCIC and CPRF.

New grants were from the Ontario Institute for Cancer Research for “Identification and characterization of genetic alterations at the stromal-epithelial interface in prostate cancer,” (with T. Brown, S. Done, L. Jurisica, G. Lockwood, J. Sweet), and from the Canadian Prostate Cancer Research Foundation for “Impact of combination antioxidants on MRI markers of cell proliferation and hypoxia among men on active surveillance with early state prostate cancer,” (with M. Haider and V. Venkateswaran) and for “Antioxidants and MRI in prostate cancer (with M. Haider). He was also co-investigator on a new grant from CIHR. He was invited speaker at meetings in Hawaii, Boca Raton, FL, Orlando, FL, Cape Town, South Africa, and Quebec City.

Dr. Michael Jewett continued his clinical and research work in many peer-reviewed funded projects in Uro-Oncology. He received the CUA/CUOG Bayer Kidney Cancer Fellowship award for Analysis of VHL gene mutation in sporadic renal cell carcinoma, (with B. Gallie, M. Ohh, and A. Evans) was co-PI with G. Fernie on an Ontario Research Commercialization Program (ORCP) ‘BioDiscover’ Stage I Business and Development Project entitled Advanced articulating patient support system for image guided therapeutics (with C. Menard, A. Finelli, and W. Kucharchyk). He was an invited speaker and/or visiting professor in Aspen, CO, the Scott Department of Urology, Baylor College of Medicine, Houston, TX, Victoria, BC, Kelowna, BC, London, ON, Amsterdam, Netherlands, the Urological Society of South Africa, Cape Town, South Africa, Interlaken, Switzerland, Riyadh, Saudi Arabia, British Association of Urological Surgeons Annual Meeting, Glasgow, Scotland, the CUA Annual Meeting, Quebec City, PQ, McMaster University in Hamilton, ON. He also won the Division of Urology AW Bruce Undergraduate Teaching award.

Dr. Michael Robinette continued as the major individual contributing to the Multi-organ transplant program at the UHN, specifically in kidney transplants.

Dr. John Trachtenberg continued his active research into novel therapies for prostate cancer with grants from CIHR, NCIC, NIH, CPRF and industry. New awards included a project funded by CIHR entitled: NIR imaging and photodynamic therapy of prostate cancer using aptamer-directed lipoprotein nanoplatform. (PI: G. Zheng, with B. Wilson). He was invited speaker at the EAU Meeting in Berlin, Germany and the VTP Symposium in Paris, France. His presentation entitled “Whole mount histological registration and validation of hierarchical clustering for segmentation of tumor and normal prostate using multi-parametric” won the Bronze Award at the MRI ISMRM Meeting. The Surgeons’ Lounge at the Toronto General Hospital was named in honour of Dr. Trachtenberg.

Dr. Tony Finelli continued his work in advancing laparoscopic urologic procedures. New grants as PI were from Bayer Inc. for “Preoperative administration of sorafenib in patients with metastatic renal cell carcinoma undergoing cytoreductive nephrectomy” (with J. Knox A. Evans, N. Fleshner, M. Jewett, T. Kim), from Pfizer for “A phase II, single arm, prospective study of neoadjuvant sutent for patients with renal cell carcinoma” (with A. Knox, A. Evans, N. Fleshner, M. Haider, M. Jewett), and from Merck for “A phase III, randomized, double-blind, placebo controlled trial of PROSCAR in men with initial negative prostate biopsies” (with N. Fleshner, M. Jewett, A. Toi, J. Trachtenberg, A. Zlotta). He was a visiting speaker in Cleveland, OH, Cancun Mexico, Baylor College of Medicine, Dallas, TX, and moderated a session at the EAU Meeting in Berlin, Germany.

UHN – Toronto Western Hospital

Dr. Magdy Hassouna continued his basic and clinical work in neurourology and neuromodulation. He chaired a session on Neuromodulation at the SUFU meeting in San Diego, CA.

Dr. Sidney Radomski, continued his role as the Urology co-ordinator in the Surgical Skills Lab. He conducted hands on sessions for the residents in various minimally topics during the year. He continued his work in peer-review and industry funded grants in incontinence, overactive bladder and erectile dysfunction.

St. Michael’s Hospital

Dr. John Honey, site chief at St. Michael’s, continued his work as Director of Endourology and the Stone Treatment Centre at SMH. He continued his clinical research studies in lithotripsy. He was course director at a Hands-on course at the American Urological Association (AUA) Meeting Anaheim, CA. He won a best poster award at the Canadian Urological Association Meeting in Quebec City and 3 best poster awards at the AUA Meeting in Anaheim, CA. He was invited faculty at the 1st International Urolithiasis Research Symposium in Indianapolis and visiting professor to the University of Ottawa.

Dr. Kenneth Pace continued his work in clinical epidemiology and Stone disease and Minimally Invasive Surgery. Dr. Pace directed the 2nd Annual Advanced Laparoscopic Urology Course in advance of Urology Update 2006. He continued his work as Chair of the IT committee for the CUA. He was appointed as the Fellowship Coordinator for the division of urology, and is the OSCE coordinator for the Phase 2 clinical clerkship surgery examination. He was an invited speaker in Indianopolis, and at an Educational Forum at the CUA meeting in Quebec City.

Dr. Robert Stewart continued as the principal urologist in the kidney transplantation program. He organized the weekly Urology Resident Postgraduate Seminars and continued as director of undergraduate surgery education at SMH.

Academic Events & Awards

The Annual Charles J. Robson Research Day was held on April 12. The Visiting Professor was Dr. Eric Klein, Professor of Surgery, Cleveland Clinic Lerner College of Medicine, Head, Section of Urologic Oncology, Glickman Urological Institute, Cleveland Clinic, Cleveland, OH.

There were over 25 presentations. Resident winners were Rohan Shahani and Rob Hamilton in the Clinical and Basic categories. Fellow winners were Sree Appu and Ahmed Haddad in similar categories. Other winners were Cengiz Yildiz in basic and Stephanie Tam in clinical.

The Patrick Harty Award for Excellence in Patient Care was awarded to Dr. Jason Lee.

Drs. Tim Davies and Michael Piannezza passed their Royal College Examinations.

Visiting Professors

Guests this year included Arie Beldegrun, UCLA, Peter Albertsen, University of Connecticut, Anthony Atala, Wake Forest University, John Denstedt, University of Western Ontario, Gary Lemack, Margaret Pearle, Claus Roehrborn, University of Texas Southwestern Medical Centre Dallas, John Mahoney, University of Ottawa, J. Curtis Nickel, Queen’s University, David Crawford, University of Colorado, Sandip Vasavada, Cleveland Clinic, Howard Snyder, University of Pennsylvania, Warren Snodgrass, Texas Tech University, Aivar Bracka, West Midlands, UK, and Paul Merguerian, Datmouth Medical School.